Veterinarian Approved Content
This content has been prepared by Doç. Dr. Mehmet ÇOLAK based on scientific sources.
Ingredient Encyclopedia

Hydrolyzed Yeast in Pet Food: MOS, Beta-Glucans, and Immune Support

Doç. Dr. Mehmet ÇOLAK 18 February 2026 131 views

Hydrolyzed yeast is used in pet food for MOS, beta-glucans, palatability, and immune support. This guide explains gut and immune relevance.


Hydrolyzed yeast is a yeast-derived ingredient produced by enzymatic hydrolysis of Saccharomyces cerevisiae. It is used as a prebiotic, palatability enhancer and immune-supportive component. The hydrolysis process releases yeast cell-wall fractions such as mannanoligosaccharides (MOS) and beta-glucans. MOS prevents pathogenic bacteria from adhering to the intestinal wall, while beta-glucans stimulate the innate immune system.

ID Card
SourceSaccharomyces cerevisiae (hydrolyzed)
Resource TypeMushroom (Processed Yeast)
FunctionPrebiotic (MOS) / Immunomodulator (β-glucan)
MOS Content15-25% (cell wall fraction)
β-Glucan Content20-35% (cell wall fraction)
Recommended Dosage0.1-0.3% formula formulation
Discussion Levellow
VetKriter Evaluation
4/5 Quality Score

Hydrolyzed yeast is a scientifically supported multifunctional ingredient. MOS and beta-glucans support digestive and immune health, while improved palatability is an additional advantage. It is generally considered a safe and beneficial additive.

Why Added?

  • Prebiotic (MOS): Prevents pathogenic bacteria (E. coli, Salmonella) from adhering to the intestinal wall
  • Immunomodulator (β-glucan): Strengthens innate immunity by activating macrophages and NK cells
  • Palatability: Umami taste and glutamic acid content increase food appeal
  • Nucleotide source: Supports cell renewal and intestinal mucosa repair
Yeast Allergy

Although rare, some animals allergy to yeast proteins can be seen. Since the hydrolysis process breaks down the protein structure, the risk of allergenicity is lower than that of brewer's yeast, but it is not completely eliminated. Yeast products should also be excluded from the elimination diet in animals with suspected food allergies.

Frequently Asked Questions

What is the difference between hydrolyzed yeast and brewer's yeast?

Brewer's yeast consists of whole yeast cells and is mainly a source of vitamin B. Hydrolyzed yeast, on the other hand, has been broken down enzymatically; cell wall components (MOS, beta-glucan) were revealed. Hydrolyzed yeast is a more functionally active prebiotic and immunomodulatory ingredient.

Related VetKriter Tools

Bibliography
  1. Swanson, K.S. et al. (2002). Supplemental fructooligosaccharides and mannanoligosaccharides influence immune function, ileal and total tract nutrient digestibilities. Journal of Nutrition, 132(5), 980-989.
  2. NRC (National Research Council). (2006). Nutrient Requirements of Dogs and Cats. National Academies Press.
Tags: hydrolyzed yeast MOS beta-glucan prebiotic immunomodulator palatability

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