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このコンテンツはDoç. Dr. Mehmet ÇOLAKが科学的資料に基づいて作成しました。
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Vitamin D (Cholecalciferol) in Pet Food: Calcium Homeostasis and Toxicity Risk

Doç. Dr. Mehmet ÇOLAK 18 2月 2026 111 回表示

Vitamin D is essential for calcium balance and bone health in pet food. This guide explains requirement ranges and toxicity concerns.


Vitamin D (cholecalciferol / D3) is an essential fat-soluble vitamin in pet food required for calcium-phosphorus homeostasis and bone health. Dogs and cats, unlike humans, cannot synthesize enough vitamin D from sunlight, so dietary intake is mandatory. Excess intake can cause severe toxicity such as hypercalcemia and soft tissue calcification.

Identity Card
Active FormCalcitriol (1,25-dihydroxy D3)
SolubilityFat-soluble (toxicity risk)
Dog Requirement500 IU/kg DM (AAFCO min.)
Cat Requirement280 IU/kg DM (AAFCO min.)
Safe Upper Limit3000 IU/kg DM (dog)
Controversy LevelModerate (Toxicity)
VetKriter Evaluation
5/5 Quality Score

Vitamin D is an essential nutrient and all complete foods should provide it adequately. Because sunlight synthesis is insufficient in dogs and cats, dietary supply is mandatory. In balanced formulas, vitamin D is usually maintained in a safe range. Extra supplementation should only be considered under veterinary supervision.

Functions

  • Calcium absorption: Increases intestinal absorption of calcium and phosphorus
  • Bone mineralization: Supports osteoblast activity and bone density
  • Immunity: Has immunomodulatory effects
  • Muscle function: Helps regulate calcium for muscle contraction
Vitamin D Toxicity

Vitamin D toxicity is a life-threatening condition. Hypercalcemia can lead to kidney failure, cardiac arrhythmias, and soft tissue calcification. Multiple pet foods were recalled in the United States in 2018-2019 because of excessive vitamin D. Additional vitamin D should never be used without veterinary oversight.

Related VetKriter Tools

References
  1. NRC (National Research Council). (2006). Nutrient Requirements of Dogs and Cats. National Academies Press.
  2. Mellanby, R. J. (2016). Beyond the skeleton: The role of vitamin D in companion animal health. Journal of Small Animal Practice, 57(4), 175-180.
タグ: ビタミンd Kolekalsiferol Kalsiyum Kemik 毒性 Hiperkalsemi

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