Mannan-oligosaccharides (MOS) are prebiotic compounds derived from the cell wall of brewer's yeast. In pet food they are valued for helping reduce pathogen attachment in the gut, supporting mucosal immunity, and improving stool quality. Their mechanism is different from fermentable fibers alone because MOS can directly interfere with the binding behavior of some undesirable bacteria.
Identity Card
| Source | Yeast cell wall (S. cerevisiae) |
| Function | Prebiotic / pathogen binding / immune support |
| Mechanism | Mannose receptor interaction |
| Use Rate | About 0.1-0.3% DM |
| Debate Level | Very low |
VetKriter Assessment
5/5 Quality Score
MOS is a premium functional ingredient with well-established prebiotic and immunomodulatory value. Its pathogen-binding role makes it more interesting than a simple marketing fiber claim when used at meaningful levels in quality formulas.
Mechanism of Action
- Pathogen binding: may reduce attachment of organisms such as E. coli and Salmonella
- IgA support: may help mucosal immune activity
- Barrier support: contributes to intestinal integrity
- Microbiome balance: helps create a healthier intestinal environment
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References
- Swanson, K. S. et al. (2002). Mannanoligosaccharides and immune function in dogs. The Journal of Nutrition, 132(5), 980-989.
- NRC. (2006). Nutrient Requirements of Dogs and Cats. National Academies Press.