Mannan-oligosaccharides (MOS) are prebiotic compounds derived from the cell wall of brewer's yeast. In pet food they are valued for helping reduce pathogen attachment in the intestine, supporting mucosal immunity, and improving stool quality. Their role is more specific than a generic fiber claim because they may interfere with the way certain undesirable bacteria bind.
Identity Card
| Source | Yeast cell wall (S. cerevisiae) |
| Function | Prebiotic / pathogen binding / immune support |
| Mechanism | Mannose receptor interaction |
| Use Rate | About 0.1-0.3% DM |
| Debate Level | Very low |
VetKriter Assessment
5/5 Quality Score
MOS is a strong functional ingredient with useful prebiotic and immune-support value. Its pathogen-binding role gives it a clearer practical benefit than many vague fiber marketing claims.
Mechanism of Action
- Pathogen binding: may reduce attachment of E. coli and Salmonella
- IgA support: may strengthen mucosal immunity
- Barrier support: helps intestinal integrity
- Microbiome balance: supports a healthier intestinal environment
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References
- Swanson, K. S. et al. (2002). Mannanoligosaccharides and immune function in dogs. The Journal of Nutrition, 132(5), 980-989.
- NRC. (2006). Nutrient Requirements of Dogs and Cats. National Academies Press.